Prof Wist is interested in the multi view integration of high fidelity molecular phenotypes to create translatable methods that can bring actionable knowledge to the clinical environment. He combines his expertise in NMR spectroscopy and his experience in cheminformatics to explore new avenues in population epidemiology and personalised healthcare. He aims at creating a pan-disease broad phenotypic databank of the world population integrating cellular, immunological, and molecular data. More specifically, he is interested the development new experiments for robust and harmonised harvesting of data and in creating open-source building blocks for knowledge extraction. His recent work revisiting established NMR experiments for spectral edition demonstrated the portability of biomarker and diagnostic signatures from high-field NMR to low-field benchtop magnets, thereby paving the way to translating an extensive body of work, in the area of phenotyping, from the laboratory to the point-of-care. Those results, published in high profile international journals, lead to the filing of 3 patents in partnership with world leading industry. As the deputy director of the ANPC, he is currently supervising the creation of a pipeline for smart storage, feature extraction, annotation, modelling, and data visualization that already includes > 200,000 molecular profiles. He is involved in international initiatives towards a more reproducible, collaborative science that fosters dissemination of knowledge irrespective of geographical location. A relevant example is the nmrium.org project that seek to improve the quality of NMR assignments by developing research-grade tool that works in the browser so they could be used for training students, but also for improving peer-reviewing by making data easily accessible for review.